Smt. Ranjani and Gayatri were born to N. Balasubramanian and Meenakshi (a Carnatic vocalist as well)  sister . Born into a Palakkad Iyer family deeply involved in classical music, Ranjani and Gayatri's musical talents were discovered at a very early age. Even as toddlers, they showed an uncanny capacity to grasp the subtle nuances of Carnatic music - Gayatri could identify over a hundred ragas when she was barely two and a half and Ranjani could delineate complex rhythm patterns at age five.

They started their violin training at the early age of nine and six respectively from Sangita Bhooshanam Prof. T.S. Krishnaswami at the Shanmukhananda Sangeeta Vidyalaya, Mumbai.

Ranjani and Gayatri began their music career as violin duet artistes even before they reached their teens. Through their intense training from Sangita Bhooshanam Prof. T. S. Krishnaswami, they quickly established themselves as top-class violinists of international repute. The sisters achieved success as violin duet performers, and subsequently they also proved successful as violin accompanists. Both Ranjani and Gayatri have accompanied various artists on the violin, including D.K. Pattammal, M Balamuralikrishna, T Vishwanathan and other popular artistes of the current generation.

The sisters have given vocal concerts since 1997, after they became students of Padma Bhushan Sangeeta Kala Acharya P. S. Narayanaswamy.