Sudhakar was born into the family of Vaggeyakara Parupalli Ramakrishnayya Pantulu, who was the guru of legendary musicians Mangalampalli Balamuralikrishna and Annavarapu Ramaswamy.  Sudhakar started learning music at GV Ramakumari. Later, he became a disciple of Annavarapu Ramaswamy.A

He presented his first vocal concert at a programme organised by Sumadhura Kalaniketan of Vijayawada. He has more than 1,000 vocal concerts to his credit and gave performances at all major cities in the country. Sudhakar who represented Andhra Pradesh at Sri Thyagaraja Swamy festival held in the United States of America.  He is now a top grade vocalist in All India Radio and Vijayawada Doordarshan Kendra. 

Sudhakar, who is also a music composer, is the court musician of Kanchi Peetham. He also holds honorary posts in NCV Sangeeta Parishad and Sangeeta Sanmandali. He established Gayaka Sarvabhouma Sangeeta Parishad to organise an annual music festival in memory of his grandfather Parupalli. Apart from giving regular vocal concerts, he also came up with `Endaro Mahanubhavuluâ, `Vaggeyakara Vibhavamâ and `Ramayana Gana Lahariâ  devotional music albums.